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Product Description
Musk Ketone CAS# 81-14-1
Ketone musk is an important synthetic fragrance with the formula C14 H18 N2 O5 and molecular weight 294.303. It is a pale yellow crystal, usually powdery or flaky, with a sweet, musk-like animal aroma, soft and long-lasting. It is insoluble in water, insoluble in ethanol, soluble in benzyl benzoate, animal oil and essential oil, melting point is 135-139 ℃, density is 1.2±0.1 g/cm3, boiling point is 369.0±42.0℃ at 760 mmHg, flash point is 153.2±20.7℃.

Product Name: | Musk ketone |
Synonyms: | 2-Acetyl-5-tert-butyl-4,6-dinitro-1,3-dimethylbenzene;3',5'-Dinitro-4'-tert-butyl-2',6'-dimethylacetophenone;3, 5-Dinitro-4-t-butyl-2, 6-dimethylacetophenone;Ketone Moschus,4-tert-Butyl-2,6-dimethyl-3,5-dinitroacetophenone, Musk ketone;Musk ketone,4-tert-Butyl-2,6-dimethyl-3,5-dinitroacetophenone, Ketone Moschus;Musk ketone 0;Ketone Moschus >=97.0% (N);1-(4-(1,1-dimethylethyl)-2,6-dimethyl-3,5-dinitrophenyl)-ethanon |
CAS: | 81-14-1 |
MF: | C14H18N2O5 |
MW: | 294.3 |
EINECS: | 201-328-9 |
Product Categories: | PP;KetonesAlphabetic;Analytical Standards;AromaticsAnalytical Standards;Chemical Class;Life Sciences Standards;Aromatic Acetophenones & Derivatives (substituted);M;METI - MZChromatography;Natural Compounds;Natural CompoundsAnalytical Standards;Nitro CompoundsChemical Class;OtherMore...Close...;Cosmetics;Food & Feed ADDITIVES;Organics |
Mol File: | 81-14-1.mol |
Musk ketone Chemical Properties |
Melting point | 134-137 °C |
Boiling point | 436.08°C (rough estimate) |
density | 1.2051 (rough estimate) |
vapor pressure | 0.001Pa at 25℃ |
refractive index | 1.5110 (estimate) |
Fp | 2 °C |
storage temp. | 2-8°C |
solubility | DMSO : 250 mg/mL (849.47 mM; Need ultrasonic) |
form | Solid |
color | White to off-white |
Odor | at 10.00 % in benzyl benzoate. fatty musk soapy dry floral powdery |
Odor Type | musk |
biological source | synthetic |
Water Solubility | Insoluble (<0.1 g/100 mL at 20 ºC) |
BRN | 2062638 |
Stability: | Stable. Incompatible with strong oxidizing agents, strong acids, strong bases. |
InChIKey | WXCMHFPAUCOJIG-UHFFFAOYSA-N |
LogP | 4.24 at 25℃ |
CAS DataBase Reference | 81-14-1(CAS DataBase Reference) |
NIST Chemistry Reference | 2,6-Dimethyl-3,5-dinitro-4-t-butylacetophenone(81-14-1) |
EPA Substance Registry System | Musk ketone (81-14-1) |
Product Usage
Musk Ketone is widely used as an important synthetic fragrance and fixative. In the flavor and fragrance industry, it is often used to prepare various flavors to give products a unique and lasting musky aroma, especially in sweet, Oriental and heavy flavor. In the field of cosmetics, it is often added to perfumes, powders, creams and other products, not only to enhance the charm of the aroma, but also to keep the aroma on the skin longer; In addition, although its application in the pharmaceutical field is limited due to toxicity and environmental hazards, in pharmacological research, it has an exciting effect on the central nervous system, respiratory center and heart, and can also promote glandular secretion, expand coronary arteries to increase coronary flow, and play a role in promoting blood circulation, reducing swelling and relieving pain.
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