D-a-Tocopherol succinate CAS#4345-03-3

D-a-Tocopherol succinate CAS#4345-03-3

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Powerful Antioxidant – Acts as a potent antioxidant, protecting cells from oxidative stress.

Radioprotective Effect – Protects against gamma-radiation by inducing granulocyte-colony stimulating factor.

Anticancer Activity – Induces apoptosis in human gastric cancer and neuroblastoma cells, and inhibits mesothelioma cell proliferation.

Regulates Cell Growth – Down-regulates fibroblast growth factor receptor-1 (FGFR-1) to inhibit tumor cell proliferation.
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Product Description

Melting point

~76 °C(lit.)

Boiling point

625.8±55.0 °C(Predicted)

Density

1.002±0.06 g/cm3(Predicted)

Vapor pressure

0Pa at 20℃

Storage temp

-20°C

Solubility

Practically insoluble in water, very soluble in methylene chloride, soluble in acetone and in anhydrous ethanol.

Form

Solid

Pka

4.35±0.17(Predicted)

Color

White or off-white

Odor

Little or no odor

Biological source

synthetic

λmax

286nm(EtOH)(lit.)

Merck

14,9495

BRN

4038233

Specific Activity

1210IU/g

Stability

Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.

LogP

12 at 25℃

CAS DataBase Reference

4345-03-3(CAS DataBase Reference)

EPA Substance Registry System

D-.alpha.-Tocopheryl acid succinate (4345-03-3)



Safety Information

WGK Germany

1

RTECS

EJ9984000

F

8-10-23

HS Code

2936280000

Toxicity

LD50 oral in rat: > 7gm/kg


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