Curcumin#458-37-7

Curcumin#458-37-7

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Curcumin#458-37-7
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Chemical Name:Curcumin
CAS No.:458-37-7
Molecular Formula:C21H20O6
Sample: Available
Mode of Transportation
1. By Air, fast but expensive.
2. By Sea, usual and economy.
3. By Train, suit for middle Asia countries.
4. By Express, suit for small package.
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Product Description


Curcumin#458-37-7

Curcumin is usually an orange-yellow crystalline powder. At room temperature, it appears bright yellow with a slight earthy smell and is odorless. At normal pressure, the boiling point is approximately 418.73°C (rough estimate). Some data also show that at a pressure of 760mmHg, the boiling point is 591.4°C. Slightly soluble in water and slightly soluble in hot water; It is readily soluble in glacial acetic acid and soluble in organic solvents such as ethanol, acetone, ether and dichloromethane.

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Curcumin Chemical Properties

Melting point

183 °C

Boiling point

418.73°C (rough estimate)

density

0.93

vapor density

13 (vs air)

refractive index

1.4155-1.4175

Fp

208.9±23.6 °C

storage temp.

2-8°C

solubility

ethanol: 10 mg/mL

form

powder

Colour Index

75300

pka

8.09(at 25℃)

color

orange

PH Range

Yellow (7.8) to red-brown (9.2)

Odor

Odorless

biological source

Curcuma longa (Turmeric)

Water Solubility

Slightly soluble (hot)

λmax

430nm

Merck

14,2673

Solvent

Ethanol

Concentration

1 mCi/ml

Specific Activity

5-15 Ci/mmol

BRN

2306965

Stability:

Stable, but may be light sensitive. Incompatible with strong oxidizing agents.

Major Application

Cosmetics, drug-eluting stents, inhibition of formation of skin-wrinkles, treating alzheimer’s disease, skin diseases, coronary restenosis, diabetes, obesity, leukemia, neurofibromas, cancer, antimicrobial, antiviral, antiinflammatory, antiprostate cancer

InChIKey

VFLDPWHFBUODDF-FCXRPNKRSA-N

LogP

3.290 (est)

CAS DataBase Reference

458-37-7(CAS DataBase Reference)

EPA Substance Registry System

Curcumin (458-37-7)


Product Usage

A natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and anti-oxidant properties. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and IκB kinase. Inhibits inducible nitric oxide synthase (iNOS), cycloxygenase and lipoxygenase. Easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nuclear envelope.

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Packaging And Shipping

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